Adrenaline has been an integral partof advanced life support since the early 1960s, but there is little evidence of whether or not its use in cardiac arrest is actually beneficial, there’s evidence that adrenaline use may lead to a poorer outcomes.


This randomised clinical controlled trial compares the effectiveness of adrenaline versus a saline placebo for the treatment of out-of-hospital cardiac arrest


London Ambulance Service
North East Ambulance Service
South East Coast Ambulance Service
Welsh Ambulance Service
West Midlands  Ambulance Service


For more information about the trial, visit the website:


If you’d like to work with ambulance services from across the UK to develop a similar project contact us.