ARREST Trial

The ARREST trial is a novel randomised-controlled trial aiming to ascertain the best post-resuscitation care pathway for patients without ST-elevation on their ECG. The study evaluates direct transfer of post-ROSC patients without ST-elevation to a Heart Attack Centre compared to transfer to the nearest Emergency Department. The trial began in January 2017 and is due Read more about ARREST Trial[…]

Airways 2

  AIRWAYS-2 was a randomised trial comparing the clinical and cost effectiveness of the i-gel supraglottic airway device with tracheal intubation in the initial airway management of patients who have suffered an out of hospital cardiac arrest (OHCA). The primary results of study have now been published here Participating Ambulance Services: East of England Ambulance Read more about Airways 2[…]

PARAMEDIC2 Almetric Score

A Randomised Trial of Epinephrine in Out-of-Hospital Cardiac Arrest This study involving five UK ambulance services and 8014 patients investigated whether using epinephrine for out-of-hospital cardiac arrest is safe and effective.  They found that using epinephrine led to improved 30-day survival compared with a placebo.  Altmetric tracks millions of mentions of 2.8 million research outputs, Read more about PARAMEDIC2 Almetric Score[…]

The PASTA Trial

This research study was a clinical trial to determine whether a Paramedic Acute Stroke Treatment Assessment (PASTA) pathway can speed up access to emergency stroke treatments, especially thrombolysis treatment, and so improve recovery after stroke.  The study ran for 3 years in three geographical areas in the UK – North East England, North West England and Wales. Read more about The PASTA Trial[…]

OHCAO- Out of Hospital Cardiac Arrest Outcomes

Supported by the European Resuscitation Council and the British Heart Foundation, the Out of Hospital Cardiac Arrest Outcomes project (OHCAO) is building Europe’s largest registry of cardiac arrests that occur outside of the hospital.   By analysing the data we will identify best practice and improve patient outcomes for those suffering out of hospital cardiac arrest.   Find Read more about OHCAO- Out of Hospital Cardiac Arrest Outcomes[…]

RIGHT-2

This randomised control trial sponsored by the British Heart Foundation assessed whether transdermal glyceryl trinitrate (GTN) is beneficial to patients experiencing a stroke. The trial completed recruitment in May 2018, and the results were published in February 2019 in The Lancet (RIGHT-2); Pre-hospital treatment with GTN for patients with presumed stroke does not appear to improve Read more about RIGHT-2[…]